Rams vs 49ers 2025: One of the NFL’s Greatest Rivalries
The Los Angeles Rams and the San Francisco 49ers share one of the most fiercely contested rivalries in the NFC West — and the 2025 NFL season delivered two unforgettable matchups between these division foes. Whether you are a Rams fan riding the blue-and-gold wave or a 49ers faithful draped in scarlet and gold, this complete breakdown of every player stat, scoring drive, and team metric from both regular-season clashes has everything you need.
The two teams met twice in the 2025 regular season. In Week 4 (Thursday Night Football, October 2, 2025), the 49ers edged the Rams in overtime at SoFi Stadium, 26–23. Then in Week 10 (November 9, 2025), the Rams got their revenge in dominant fashion at Levi’s Stadium, routing San Francisco 42–26. Below, we go deep on both games with full team stats, individual player performance highlights, scoring plays, and historical context.
2025 Season Series at a Glance
| Game | Date | Location | Winner | Final Score |
|---|---|---|---|---|
| Game 1 (Week 4) | Oct 2, 2025 | SoFi Stadium (OT) | San Francisco 49ers | 26–23 |
| Game 2 (Week 10) | Nov 9, 2025 | Levi’s Stadium | Los Angeles Rams | 42–26 |
GAME 1 — WEEK 4
San Francisco 49ers 26 — Los Angeles Rams 23 (OT) | October 2, 2025 | SoFi Stadium
Game 1 Team Stats: Rams vs 49ers (Week 4)
The first meeting of the 2025 season was a classic NFC West battle that went to overtime, with San Francisco’s kicker delivering the walk-off field goal. Matthew Stafford aired it out for 389 passing yards on 30-of-47, but two critical fumbles gave the 49ers the extra possessions they needed. The Rams dominated through the air yet were undone by their own turnovers.
| Team Stat | LA Rams | SF 49ers |
|---|---|---|
| Final Score | 23 | 26 (OT) |
| Total Yards | 456 | 407 |
| Passing Yards | 389 | 342 |
| Rushing Yards | 78 | 74 |
| Plays | 64 | 83 |
| Time of Possession | 26:20 | 40:04 |
| First Downs | 27 | 27 |
| Turnovers | 2 | 0 |
| Penalties | 5 / 36 yds | 8 / 44 yds |
| 3rd Down Conversion | — | — |
| Sacks | 1 | 1 |
| Touchdowns | 3 | 2 |
| Field Goals Made | 1/2 | 4/4 |
| Passer Rating (QB) | 111.0 | 100.9 |
Game 1 Scoring Drives (Play-by-Play Summary)
The game was a back-and-forth affair decided by San Francisco’s perfect 4-for-4 field goal performance from Jake Elliott, including a clutch 59-yarder late in the fourth quarter and the game-winner in overtime.
| Quarter | Time | Team | Play | Score |
|---|---|---|---|---|
| Q1 | 10:12 | SF 49ers | M. Jones pass to J. Tonges, 6 yds TD | SF 7 – LA 0 |
| Q2 | 13:47 | SF 49ers | M. Jones pass to C. McCaffrey, 1 yd TD | SF 14 – LA 0 |
| Q2 | 2:15 | LA Rams | M. Stafford pass to K. Williams, 14 yds TD | SF 14 – LA 7 |
| Q2 | 0:02 | SF 49ers | E. Pineiro 37-yd FG | SF 17 – LA 7 |
| Q3 | 6:36 | SF 49ers | E. Pineiro 20-yd FG | SF 20 – LA 7 |
| Q3 | 3:48 | LA Rams | M. Stafford pass to P. Nacua, 1 yd TD | SF 20 – LA 14 |
| Q4 | 10:43 | LA Rams | M. Stafford pass to K. Williams, 8 yds TD | Tied 20–20 |
| Q4 | 4:07 (approx) | LA Rams | J. Karty XP blocked (score remains 20) | Tied 20–20 |
| Q4 | 2:57 | SF 49ers | E. Pineiro 59-yd FG | SF 23 – LA 20 |
| Q4 | 0:06 | LA Rams | J. Karty 48-yd FG | Tied 23–23 |
| OT | — | SF 49ers | E. Pineiro 41-yd FG (Walk-off) | FINAL: SF 26 – LA 23 |
Game 1 Key Player Performances — Los Angeles Rams
Matthew Stafford put up massive numbers through the air (389 yards, 3 TDs), making a strong case for the Rams in this game, but the turnover bug cost Los Angeles dearly. Kyren Williams was productive on limited carries, and Puka Nacua continued his ascent as a reliable red-zone target.
| Rams Player | Position | Key Stat Line |
|---|---|---|
| Matthew Stafford | QB | 30/47, 389 passing yds, 3 TD, 0 INT, 111.0 passer rating |
| Kyren Williams | RB | Team’s primary rusher; 78 rushing yards on 16 attempts (team) |
| Puka Nacua | WR | Red-zone TD catch (1 yd); 389 total team receiving yards |
| Demarcus Robinson / Kupp | WR/TE | Combined to accumulate bulk of receiving yards |
| Jake Karty | K | Hit the crucial 48-yd FG to force OT; had an XP blocked |
Game 1 Key Player Performances — San Francisco 49ers
Mason Jones managed the game efficiently with a 100.9 passer rating. Christian McCaffrey remained a nightmare in the red zone. Jake Elliott was the hero of the day, going a perfect 4-for-4 on field goals, including the dramatic 59-yarder and the overtime winner.
| 49ers Player | Position | Key Stat Line |
|---|---|---|
| Mason Jones | QB | 33/49, 342 passing yds, 2 TD, 0 INT, 100.9 passer rating |
| Christian McCaffrey | RB/WR | 1-yd TD reception in Q2; key red-zone weapon (33 total team rush attempts) |
| Jake Elliott | K | 4/4 FGs (22, 20, 37, 59-yd + 41-yd OT walk-off); 15 total points |
| Jordan Jennings / Jonah Tonges | TE/WR | Tonges 6-yd TD catch in Q1 |
| 49ers Defense | Team | Forced 2 Rams fumbles; 0 turnovers committed |
GAME 2 — WEEK 10
Los Angeles Rams 42 — San Francisco 49ers 26 | November 9, 2025 | Levi’s Stadium
Game 2 Team Stats: Rams vs 49ers (Week 10)
If Game 1 belonged to San Francisco, Game 2 was entirely the Rams’ masterpiece. Los Angeles came into Levi’s Stadium and erupted for 42 points — their most in any rivalry game in recent memory. Matthew Stafford threw for 4 touchdowns, Kyren Williams added 2 rushing scores, and the Rams defense picked off the ball once and even blocked a two-point conversion attempt. A flawless outing with zero penalties and zero turnovers sealed the dominant road win.
| Team Stat | LA Rams | SF 49ers |
|---|---|---|
| Final Score | 42 | 26 |
| Total Yards | 401 | 393 |
| Passing Yards | 280 | 319 |
| Rushing Yards | 126 | 74 |
| Time of Possession | 32:32 | 27:28 |
| Plays | 67 | 60 |
| First Downs | 31 | 24 |
| Turnovers | 0 | 2 |
| Penalties | 0 (0 yds) | 7 (45 yds) |
| Sacks Taken | 1 | 0 |
| Touchdowns | 6 | 4 |
| Field Goals | 0/0 | 0/0 |
| Passer Rating (QB) | 127.1 | 115.7 |
| Avg Gain Per Play | 6.0 | 6.6 |
| Fumbles Lost | 0 | 1 |
| INT Thrown | 0 | 1 |
Game 2 Scoring Drives (Play-by-Play Summary)
The Rams came out firing and never looked back. After jumping to a 14-0 lead in the first quarter, Los Angeles extended their advantage to 28-7 before San Francisco managed a rally attempt in the third quarter. However, Stafford’s fourth quarter heroics — including two TD drives — put the game away.
| Quarter | Time | Team | Play | Score |
|---|---|---|---|---|
| Q1 | 10:18 | LA Rams | K. Williams rush left tackle, 2 yds TD | LA 7 – SF 0 |
| Q1 | 5:41 | LA Rams | M. Stafford pass to P. Nacua, 22 yds TD | LA 14 – SF 0 |
| Q2 | 13:48 | LA Rams | M. Stafford pass to D. Allen, 4 yds TD | LA 21 – SF 0 |
| Q2 | 3:19 | SF 49ers | M. Jones pass to J. Jennings, 6 yds TD | LA 21 – SF 7 |
| Q3 | 9:37 | SF 49ers | B. Robinson rush up middle, 1 yd TD | LA 21 – SF 14 |
| Q3 | 2:44 | LA Rams | M. Stafford pass to D. Adams, 2 yds TD | LA 28 – SF 14 |
| Q4 | 12:36 | SF 49ers | M. Jones pass to L. Farrell, 9 yds TD (XP blocked) | LA 28 – SF 20 |
| Q4 | 10:07 | LA Rams | K. Williams rush left tackle, 7 yds TD | LA 35 – SF 20 |
| Q4 | 5:17 | LA Rams | M. Stafford pass to C. Parkinson, 16 yds TD | LA 42 – SF 20 |
| Q4 | 3:05 | SF 49ers | M. Jones pass to G. Kittle, 13 yds TD; 2-pt att. intercepted | FINAL: LA 42 – SF 26 |
Game 2 Key Player Performances — Los Angeles Rams
Matthew Stafford delivered one of his signature performances: 4 touchdown passes, zero interceptions, and a passer rating of 127.1. Kyren Williams contributed 2 rushing touchdowns and led the ground game. Notably, the Rams committed zero penalties the entire game — a remarkable feat of discipline in a rivalry match on the road.
| Rams Player | Position | Key Stat Line |
|---|---|---|
| Matthew Stafford | QB | 24/36, 280 passing yds, 4 TD, 0 INT, 127.1 passer rating |
| Kyren Williams | RB | 2 rushing TDs (2 yd, 7 yd); part of team’s 126 rush yards |
| Puka Nacua | WR | 22-yd TD reception (Q1); key deep threat all game |
| Davante Adams | WR | 2-yd TD reception (Q3); 142 team yards after catch (receiving) |
| Demarcus Allen | TE | 4-yd TD reception (Q2); red-zone target |
| Cole Parkinson | TE | 16-yd TD reception (Q4); sealed the victory |
| Rams Defense | Team | 1 INT, blocked 2-pt conversion, 1 forced fumble, 0 penalties |
| Holton Mevis | K | 6-for-6 on PATs |
Game 2 Key Player Performances — San Francisco 49ers
Despite the lopsided scoreline, Mason Jones had a strong statistical day with a 115.7 passer rating and 319 yards through the air on 33 completions. George Kittle found the end zone in garbage time, and the 49ers’ offense was actually productive yardage-wise — but turnovers and a penalty-heavy approach proved costly.
| 49ers Player | Position | Key Stat Line |
|---|---|---|
| Mason Jones | QB | 33/39, 319 passing yds, 3 TD, 1 INT, 115.7 passer rating |
| George Kittle | TE | 13-yd TD reception (Q4); team-leading red-zone target |
| Jordan Jennings | WR | 6-yd TD reception (Q2); led early 49ers response |
| Luke Farrell | TE | 9-yd TD reception (Q4) |
| Brock Robinson | RB | 1-yd rushing TD (Q3); held down the run game |
| 49ers Defense | Team | 84.6% completion allowed to Stafford; struggled containing Rams’ TE corps |
Head-to-Head Season Stats: Rams vs 49ers (Combined Both Games)
Looking at both games together, the Rams and 49ers were remarkably even in total yardage across the season series. The Rams won the series 1–1, with the split decided largely by turnover differentials and the Rams’ ability to protect the football in Week 10.
| Season Series Stat | LA Rams (Total) | SF 49ers (Total) |
|---|---|---|
| Games Won | 1 | 1 |
| Total Points Scored | 65 | 52 |
| Total Passing Yards | 669 | 661 |
| Total Rushing Yards | 204 | 148 |
| Total Yards | 857 | 800 |
| Combined TDs | 9 | 6 |
| Combined Turnovers | 2 | 2 |
| Total Penalties (Yards) | 5 (36 yds) | 15 (89 yds) |
| Passer Rating (Avg) | 119.1 | 108.3 |
| Field Goals Made | 1/2 | 4/4 |
| Sacks Taken (Season Series) | 2 | 1 |
Matthew Stafford: Statistical Deep Dive (Both Games)
Matthew Stafford was the Rams’ consistent performer across both rivalry games. His numbers grew significantly from Game 1 to Game 2 as he ironed out the turnover issues and delivered a near-flawless performance the second time around.
| Stafford Stat | Game 1 (Week 4 — Loss) | Game 2 (Week 10 — Win) |
|---|---|---|
| Completions / Attempts | 30 / 47 | 24 / 36 |
| Completion % | 63.8% | 66.7% |
| Passing Yards | 389 | 280 |
| Touchdowns | 3 | 4 |
| Interceptions | 0 | 0 |
| Sacks Taken | 1 | 1 |
| Passer Rating | 111.0 | 127.1 |
| Avg Yards Per Attempt | 7.88 | 7.43 |
| Net Passing Yards | 378 | 275 |
| Air Yards | 269 | 138 |
Across both games, Stafford passed for 669 yards and 7 touchdowns with zero interceptions — an outstanding series that underscored his value as one of the NFL’s premier signal-callers. His combined passer rating of roughly 119 over the two games was among the best in the league for any quarterback in a two-game span during the 2025 season.
Mason Jones (49ers QB): Statistical Deep Dive (Both Games)
| Jones Stat | Game 1 (Week 4 — Win) | Game 2 (Week 10 — Loss) |
|---|---|---|
| Completions / Attempts | 33 / 49 | 33 / 39 |
| Completion % | 67.3% | 84.6% |
| Passing Yards | 342 | 319 |
| Touchdowns | 2 | 3 |
| Interceptions | 0 | 1 |
| Passer Rating | 100.9 | 115.7 |
| Avg Yards Per Attempt | 6.66 | 8.18 |
| Sacks Taken | 1 | 0 |
Jones was productive in both meetings, managing a combined 661 passing yards, 5 touchdowns, and 1 interception. His completion percentage skyrocketed in Game 2 (84.6%), but with the Rams defense stepping up and his team committing a crucial fumble, even efficiency could not overcome a dominant Rams offensive showing.
Defensive Performance Breakdown
Los Angeles Rams Defense
| Defensive Stat | Game 1 (Week 4) | Game 2 (Week 10) |
|---|---|---|
| Tackles (Solo) | 48 | 35 |
| Assists | 34 | 32 |
| Sacks | 1.0 (9 yds) | 0 |
| Interceptions | 0 | 1 |
| Passes Defended | 5 | 5 |
| Forced Fumbles | 0 | 1 |
| Fumble Recoveries | 0 | 1 |
| QB Hits | 10 | 1 |
| Tackles for Loss | 3.0 | 2.0 |
| Missed Tackles | 9 | 8 |
| Blitzes | 8 | 8 |
| 4th Down Stops | 1 | 2 |
| Defensive Conversions | 0 | 1 (2-pt att. intercepted) |
San Francisco 49ers Defense
| Defensive Stat | Game 1 (Week 4) | Game 2 (Week 10) |
|---|---|---|
| Tackles (Solo) | 28 | 29 |
| Assists | 26 | 36 |
| Sacks | 1.0 (11 yds) | 1.0 (5 yds) |
| Interceptions | 0 | 0 |
| Passes Defended | 4 | 3 |
| Forced Fumbles | 1 | 0 |
| Fumble Recoveries | 2 | 0 |
| QB Hits | 2 | 8 |
| Tackles for Loss | 1.0 | 3.0 |
| Missed Tackles | 2 | 5 |
| Blitzes | 8 | 19 |
| 4th Down Stops | 0 | 0 |
| Special Teams Block | 1 (XP) | 1 (XP) |
The Rams–49ers NFC West Rivalry: Historical Context
The Los Angeles Rams and San Francisco 49ers have been division rivals since the Rams relocated from St. Louis in 2016. What was once a one-sided affair became one of the league’s premier matchups as both franchises loaded up on talent and competed for multiple Super Bowl berths. The Rams won Super Bowl LVI in February 2022, while the 49ers have reached multiple NFC Championship Games in recent years, creating a back-and-forth power struggle that defines the NFC West landscape.
In the 2025 season, the series ended 1–1, with each team winning on the road — a theme that has characterized this rivalry, where home-field advantage often means little when these two meet. The Rams’ Week 10 road blowout (42–26 at Levi’s Stadium) was one of the most lopsided results in the recent history of this series.
2025 Season Records Context
The Rams finished the 2025 regular season with a strong record, advancing deep into the playoffs before being eliminated by Seattle in the Divisional round. San Francisco, meanwhile, battled injuries and inconsistency all season, finishing with a Wild Card appearance. The pair met exactly twice — Week 4 and Week 10 — with the 49ers taking the early match in overtime and the Rams dominating the rematch.
Key Takeaways & Analysis
1. Stafford vs. Jones: The QB Battle
Stafford outperformed Jones in the stat that matters most — touchdowns — across both games, throwing 7 TDs to Jones’s 5. More importantly, Stafford’s zero-interception performance in both games, combined with his Week 10 passer rating of 127.1, gave the Rams a clear edge at the game’s most important position.
2. Turnovers Were the Series Differentiator
The Rams turned the ball over twice in Game 1 (both fumbles), which directly led to San Francisco points. In Game 2, the Rams committed zero turnovers, and the 49ers coughed it up twice. The direct correlation between turnover margin and game outcome could not have been more stark across these two games.
3. Jake Elliott: The Unsung Hero of Game 1
Elliott’s perfect 4-for-4 field goal performance — highlighted by a 59-yarder in Q4 and the overtime game-winner — was the defining individual performance of Game 1. Without him, the 49ers lose. He also blocked a Rams PAT, further swinging the special teams battle.
4. Penalties Defined the Series
Across both games, the 49ers were flagged 15 times for 89 yards — including 7 costly penalties in Game 2 — compared to the Rams’ 5 flags for 36 yards total. The Rams were remarkable in Week 10, committing zero penalties in a road rivalry game, a testament to their discipline and preparation.
5. Kyren Williams — A Dual-Threat Weapon
Williams’ two rushing touchdowns in Game 2 showed the Rams’ ability to punish the 49ers defense on the ground when needed. The Rams averaged a healthy 4.2 yards per carry in Game 2 while controlling the clock with 32 minutes of possession.
Frequently Asked Questions — Rams vs 49ers 2025
Q: Who won the Rams vs 49ers 2025 season series?
The series ended 1–1. San Francisco won Game 1 in Week 4 (26–23 in overtime), and Los Angeles won Game 2 in Week 10 (42–26).
Q: What were Matthew Stafford’s stats vs the 49ers in 2025?
Across both games, Stafford went 54-of-83 for 669 yards, 7 touchdowns, and 0 interceptions, with passer ratings of 111.0 and 127.1 respectively.
Q: What happened in the Rams 49ers overtime game (Week 4, 2025)?
Jake Elliott kicked the game-winning 41-yard field goal in overtime after both teams were tied 23–23 at the end of regulation. Elliott was perfect on all 4 field goal attempts, including a 59-yarder in the fourth quarter. The Rams lost despite Stafford throwing for 389 yards and 3 touchdowns.
Q: How did the Rams beat the 49ers 42-26 in Week 10?
The Rams scored six touchdowns, committed zero penalties and zero turnovers, and received 4 TD passes from Stafford and 2 rushing TDs from Kyren Williams. The 49ers, by contrast, turned the ball over twice and were flagged 7 times. Los Angeles led 14-0 after one quarter and never relinquished the lead.
Q: Who scored touchdowns in the Rams vs 49ers games (2025)?
Rams TDs in both games: Kyren Williams (3 rushing TDs), Puka Nacua (2 receiving TDs), Demarcus Allen (1 TD), Davante Adams (1 TD), Cole Parkinson (1 TD). 49ers TDs: Jonah Tonges, Christian McCaffrey, Jordan Jennings, Brock Robinson, Luke Farrell, George Kittle.
Conclusion
The 2025 Rams vs 49ers season series was everything that NFL fans expect from this rivalry: a dramatic overtime thriller in Game 1 and a dominant road blowout in Game 2. Matthew Stafford’s elite play across both games, combined with the Rams’ zero-turnover, zero-penalty masterclass in Week 10, established Los Angeles as the stronger team in the second half of the season.
San Francisco proved they could grind out a win in overtime with disciplined special teams, but their penalty issues and inability to protect the ball in the rematch cost them the season sweep. As both franchises look toward future drafts and free agency periods, one thing is certain: the NFC West rivalry between the Rams and 49ers will continue to produce some of the most compelling football in the NFL.
Article based on official NFL 2025 regular season game data. All statistics sourced from NFL/SportRadar official records.
